resultados 1 - 2 para la consulta:Neurosteroid

2 documentos corresponden a la consulta.

Palabras contadas: neurosteroid: 4

Synthesis of D-homo analogs of neurosteroids

Di Chenna, P. - Ghini, A.A. - Burton, G.

Molecules 2000;5(3):447-448

2000

Temas: 11alpha hydroxyprogesterone - 3alpha hydroxy 5alpha pregnan 20 one derivative - cyclopropylketone derivative - dehydropregnenolone acetate - ketone derivative - mercury derivative - neurosteroid derivative - pregnenolone derivative - steroid - unclassified drug

Descripción: 17(13→18)-Abeo and D-homo analogs of the natural neurosteroid 3α-hydroxy-5αH-pregnan-20-one were prepared by anionic or radical (mercury (II) hydride mediated) rearrangements of steroidal cyclopropylketones respectively.

Tipo de documento: info:ar-repo/semantics/artículo

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Oxido-bridged neurosteroid analogues. Synthesis of 2,19-oxido-allopregnanolone

Eduardo, S.L. - Ghini, A.A. - Burton, G.

Arkivoc 2003;2003(10):468-476

2003

Temas: 2,19-Oxido-allopregnanolone - 4,19-oxido-allopregnanolone - Neurosteroid - Oxido-bridged steroid - 19 hydroxy 2alpha,3alpha epoxypregnane - 19 hydroxypregnenolone 3 acetate - 3alpha hydroxy 2,19 oxido 5alphah pregnan 20 one - 3alpha hydroxy 5alphah pregnan 20 one - 4beta,19 oxido 3alpha hydroxy 5alphah pregnan 20 one - bridged compound

Descripción: 3α-Hydroxy-2,19-oxido-5αH-pregnan-20-one was synthesized in 6 steps from the easily available 19-hydroxypregnenolone 3-acetate. The 2,19-oxido bridge was formed in a single step upon spontaneous cyclization and desilylation of a TBDMS protected 19-hydroxy-2α,3α-epoxypregnane. The 4,19-oxido analogue was obtained as a byproduct upon cyclization of the isomeric 3α,4α-epoxide.

Tipo de documento: info:ar-repo/semantics/artículo

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