1 documento corresponde a la consulta.
Palabras contadas: 5alphah: 3, 3alpha: 4, pregnan: 4, hydroxy: 10, 20: 72, one: 452
Eduardo, S.L. - Ghini, A.A. - Burton, G.
Arkivoc 2003;2003(10):468-476
2003
Temas: 2,19-Oxido-allopregnanolone - 4,19-oxido-allopregnanolone - Neurosteroid - Oxido-bridged steroid - 19 hydroxy 2alpha,3alpha epoxypregnane - 19 hydroxypregnenolone 3 acetate - 3alpha hydroxy 2,19 oxido 5alphah pregnan 20 one - 3alpha hydroxy 5alphah pregnan 20 one - 4beta,19 oxido 3alpha hydroxy 5alphah pregnan 20 one - bridged compound
Descripción: 3α-Hydroxy-2,19-oxido-5αH-pregnan-20-one was synthesized in 6 steps from the easily available 19-hydroxypregnenolone 3-acetate. The 2,19-oxido bridge was formed in a single step upon spontaneous cyclization and desilylation of a TBDMS protected 19-hydroxy-2α,3α-epoxypregnane. The 4,19-oxido analogue was obtained as a byproduct upon cyclization of the isomeric 3α,4α-epoxide.
...ver más Tipo de documento: info:ar-repo/semantics/artículo