Descripción: Isotopic age determinations (40Ar/39Ar) and associated magnetic polarity stratigraphy for Casamayoran age fauna at Gran Barranca (Chubut, Argentina) indicate that the Barrancan 'subage' of the Casamayoran South American Land Mammal 'Age' is late Eocene, 18 to 20 million years younger than hitherto supposed. Correlations of the radioisotopically dated magnetic polarity stratigraphy at Gran Barranca with the Cenozoic geomagnetic polarity time scale indicate that Barrancan faunal levels at the Gran Barranca date to within the magnetochronologic interval from 35.34 to 36.62 megannums (Ma) or 35.69 to 37.60 Ma. This age revision constrains the timing of an adaptive shift in mammalian herbivores toward hypsodonty. Specifically, the appearance of large numbers of hypsodont taxa in South America occurred sometime between 36 and 32 Ma (late Eocene-early Oligocene), at approximately the same time that other biotic and geologic evidence has suggested the Southern high latitudes experienced climatic cooling associated with Antarctic glaciation.

Descripción: The small community of the Tomárâho, an ethnic group culturally derived from the Zamucos, have become known in the South American and world anthropological scenario in recent times. This group, far from the banks of the Paraguay river, remained concealed from organized modern societies for many years. Like any other groups of people in close contact with nature, the Tomárâho developed a profound and rich world-view which parallels other more widely researched aboriginal cultures as well as showing distinctive features of their own. This is also apparent in their imagery of the sky and of the characters that are closely connected with the celestial sphere. This paper is based on the lengthy anthropological studies of G. Sequera. We have recently undertaken a project to carry out a detailed analysis of the different astronomical elements present in the imagined sky of the Tomárâho and other Chamacoco ethnic groups. We will briefly review some aspects of this aboriginal culture: places where they live, regions of influence in the past, their linguistic family, their living habits and how the advancement of civilization affected their culture and survival. We will later mention the fieldwork carried out for decades and some of the existing studies and publications. We will also make a brief description of the methodology of this work and special anthropological practices. Last but not least, we will focus on the Tomárâho conception of the sky and describe the research work we have been doing in recent times. © International Astronomical Union 2011.

Descripción: The proopiomelanocortin gene (POMC) is expressed in the pituitary gland and the ventral hypothalamus of all jawed vertebrates, producing several bioactive peptides that function as peripheral hormones or central neuropeptides, respectively. We have recently determined that mouse and human POMC expression in the hypothalamus is conferred by the action of two 5′ distal and unrelated enhancers, nPE1 and nPE2. To investigate the evolutionary origin of the neuronal enhancer nPE2, we searched available vertebrate genome databases and determined that nPE2 is a highly conserved element in placentals, marsupials, and monotremes, whereas it is absent in nonmammalian vertebrates. Following an in silico paleogenomic strategy based on genome-wide searches for paralog sequences, we discovered that opossum and wallaby nPE2 sequences are highly similar to members of the superfamily of CORE-short interspersed nucleotide element (SINE) retroposons, in particular to MAR1 retroposons that are widely present in marsupial genomes. Thus, the neuronal enhancer nPE2 originated from the exaptation of a CORE-SINE retroposon in the lineage leading to mammals and remained under purifying selection in all mammalian orders for the last 170 million years. Expression studies performed in transgenic mice showed that two nonadjacent nPE2 subregions are essential to drive reporter gene expression into POMC hypothalamic neurons, providing the first functional example of an exapted enhancer derived from an ancient CORE-SINE retroposon. In addition, we found that this CORE-SINE family of retroposons is likely to still be active in American and Australian marsupial genomes and that several highly conserved exonic, intronic and intergenic sequences in the human genome originated from the exaptation of CORESINE retroposons. Together, our results provide clear evidence of the functional novelties that transposed elements contributed to their host genomes throughout evolution. © 2007 Santangelo et al.